DB Group @ MIT ChemE

Research in Colloid and Interface Science

Publications

2008

Kushner-IV, J., Blankschtein, D., Langer, R.: Evaluation of hydrophilic permeant transport parameters in the localized and non-localized transport regions of skin treated simultaneously with low-frequency ultrasound and sodium lauryl sulfate, Journal of Pharmaceutical Sciences 97, 906-918 (2008).
Kushner-IV, J., Blankschtein, D., Langer, R.: Heterogeneity in skin treated with low-frequency ultrasound, Journal of Pharmaceutical Sciences 97, 4119-4128 (2008).
Stephenson, B.C., Stafford, K.A., Beers, K.J., Blankschtein, D.: Application of computer simulation free-energy methods to compute the free energy of micellization as a function of micelle composition. 1. Theory, Journal of Physical Chemistry B 112, 1634-1640 (2008).
Stephenson, B.C., Goldsipe, A., Blankschtein, D.: Molecular dynamics simulation and thermodynamic modeling of the self-assembly of the triterpenoids asiatic acid and madecassic acid in aqueous solution, Journal of Physical Chemistry B 112, 2357-2371 (2008).
Ghosh, S., Kim, D., So, P., Blankschtein, D.: Visualization and quantification of skin barrier perturbation induced by surfactant-humectant systems using two-photon fluorescence microscopy, Journal of Cosmetic Science 59, 263-289 (2008).
Stephenson, B.C., Stafford, K.A., Beers, K.J., Blankschtein, D.: Application of computer simulation free-energy methods to compute the free energy of micellization as a function of micelle composition. 2. Implementation, Journal of Physical Chemistry B 112, 1641-1656 (2008).

2007

Kushner-IV, J., Deen, W., Blankschtein, D., Langer, R.: First-principles, structure-based transdermal transport model to evaluate lipid partition and diffusion coefficients of hydrophobic permeants solely from stratum corneum permeation experiments, Journal of Pharmaceutical Sciences 96, 3236-3251 (2007).
Kushner-IV, J., Kim, D., So, P.T.C., Blankschtein, D., Langer, R.S.: Dual-channel two-photon microscopy study of transdermal transport in skin treated with low-frequency ultrasound and a chemical enhancer, Journal of Investigative Dermatology 127, 2832-2846 (2007).
Kushner-IV, J., Blankschtein, D., Langer, R.: Evaluation of the porosity, the tortuosity, and the hindrance factor for the transdermal delivery of hydrophilic permeants in the context of the aqueous pore pathway hypothesis using dual-radiolabeled permeability experiments, Journal of Pharmaceutical Sciences 96, 3263-3282 (2007).
Ghosh, S., Hornby, S., Grove, G., Zerwick, C., Appa, Y., Blankschtein, D.: Ranking of aqueous surfactant-humectant systems based on an analysis of in vitro and in vivo skin barrier perturbation measurements, Journal of Cosmetic Science 58, 599-620 (2007).
Goldsipe, A., Blankschtein, D.: Molecular-thermodynamic theory of micellization of multicomponent surfactant mixtures: 1. Conventional (pH-insensitive) surfactants, Langmuir 23, 5942-5952 (2007).
Stephenson, B.C., Goldsipe, A., Beers, K.J., Blankschtein, D.: Quantifying the hydrophobic effect. 1. A computer simulation-molecular- thermodynamic model for the self-assembly of hydrophobic and amphiphilic solutes in aqueous solution, Journal of Physical Chemistry B 111, 1025-1044 (2007).
Stephenson, B.C., Beers, K.J., Blankschtein, D.: Quantifying the hydrophobic effect. 3. A computer simulation - Molecular-thermodynamic model for the micellization of ionic and zwitterionic surfactants in aqueous solution, Journal of Physical Chemistry B 111, 1063-1075 (2007).
Stephenson, B.C., Goldsipe, A., Beers, K.J., Blankschtein, D.: Quantifying the hydrophobic effect. 2. A computer simulation-molecular- thermodynamic model for the micellization of nonionic surfactants in aqueous solution, Journal of Physical Chemistry B 111, 1045-1062 (2007).
Ghosh, S., Blankschtein, D.: The role of sodium dodecyl sulfate (SDS) micelles in inducing skin barrier perturbation in the presence of glycerol, Journal of Cosmetic Science 58, 109-133 (2007).
Ghosh, S., Blankschtein, D.: Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores, Journal of Cosmetic Science 58, 229-244 (2007).
Goldsipe, A., Blankschtein, D.: Molecular-thermodynamic theory of micellization of multicomponent surfactant mixtures: 2. pH-sensitive surfactants, Langmuir 23, 5953-5962 (2007).

2006

Mazzola, P.G., Lam, H., Kavoosi, M., Haynes, C.A., A. Jr., P., Penna, T.C.V., Wang, D.I.C., Blankschtein, D.: Affinity-tagged green fluorescent protein (GFP) extraction from a clarified E. coli cell lysate using a two-phase aqueous micellar system, Biotechnology and Bioengineering 93, 998-1004 (2006).
Goldsipe, A., Blankschtein, D.: Molecular-thermodynamic theory of micellization of pH-sensitive surfactants, Langmuir 22, 3547-3559 (2006).
Moorkanikkara, S.N., Blankschtein, D.: Short-time behavior of mixed diffusion-barrier controlled adsorption, Journal of Colloid and Interface Science 296, 442-457 (2006).

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